Familial aggregation of undifferentiated spondyloarthropathy associated with HLA-B7.

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Familial aggregation of undifferentiated spondyloarthropathy associated with HLA-B7.

OBJECTIVE To report multiple cases of recurrent seronegative arthropathy, enthesopathy, or both, occurring in a single family in the absence of the HLA-B27 tissue type, coexistent psoriasis or inflammatory bowel disease. METHODS Three generations of one family together with their general practitioners completed a standard questionnaire. All subjects with a positive questionnaire and two rando...

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HLA-B27 associated spondyloarthropathy and severe ascending aortitis.

We describe a young woman who developed early and severe aortic regurgitation and subsequent aortitis with aneurysm formation requiring surgery.

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Familial Mediterranean fever-related spondyloarthropathy

Familial Mediterranean fever (FMF) is an autosomal recessively-transmitted disease characterised by attacks of fever and serositis. Articular involvement is the second most common manifestation following abdominal pain. Patients with FMF are considered to have an increased risk of sacroiliitis, while the association of such abnormalities with FMF has not been accepted uniformly. We report two c...

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HLA-B27 associated spondyloarthropathy, an autoimmune disease based on crossreactivity between bacteria and HLA-B27?

Most autoimmune diseases are associated with certain HLA types. Therefore, spondyloarthropathies (SpA) strongly associated with HLA-B27, are also often classified as autoimmune diseases. This study questions whether SpA indeed fulfils the criteria of an autoimmune disease. The Medline database was searched for all reports between 1966 and April 1998 on the presence of autoimmune reactivity in S...

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Is undifferentiated seronegative spondyloarthropathy a forme fruste of reactive arthritis?

Undifferentiated spondyloarthropathy (USpa) may either represent a forme fruste of other spondyloarthropathies like reactive arthritis or be a different disease entity. To study the link between USpa and reactive arthritis, we studied the presence of IgA antibodies to Yersinia enterocolitica, Salmonella typhimurium, Shigella flexneri, Campylobacter jejuni and Chlamydia trachomatis in sera from ...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1995

ISSN: 0003-4967

DOI: 10.1136/ard.54.2.125